ICS DB12 DB Determination of five kinds of artificial sweeteners in drinking water liquid chromatography-tandem mass spectrometry method – — — μ — μ μ μ μ — X C 11000 200 — — AA — BB 100ng/mL 20160501std16 MRM of 8 Channels ESTIC 1.67e5 1.33 100 % 1.96 1.57 1.88 1.45 3.81 0 Time 0.25 0.50 0.75 1.00 1.25 1.50 1.75 2.00 2.25 2.50 2.75 3.00 3.25 3.50 3.75 4.00 4.25 4.50 4.75 100ng/mL 20160502T3std1-6 MRM of 8 Channels ES395 > 395 (sanlvzhetang) 1.18e5 1.95 % 100 3.763.77 3.50 0 0.20 20160502T3std1-6 0.40 0.60 0.80 1.00 1.20 1.40 1.60 1.80 2.00 2.20 2.40 2.60 2.80 3.00 3.20 3.40 3.60 3.80 4.00 4.20 4.40 4.60 4.80 MRM of 8 Channels ES292.9 > 260.9 (asibatian) 5.70e4 2.00 2.20 2.40 2.60 2.80 3.00 3.20 3.40 3.60 3.80 4.00 4.20 4.40 4.60 4.80 MRM of 8 Channels ES292.9 > 200.1 (asibatian) 2.68e4 1.86 % 100 0 0.20 20160502T3std1-6 0.40 0.60 0.80 1.00 1.20 1.40 1.60 1.80 1.85 % 100 0 0.20 20160502T3std1-6 0.40 0.60 0.80 1.00 1.20 1.40 1.60 1.80 2.00 2.20 2.40 2.60 2.80 3.00 3.20 3.40 3.60 3.80 4.00 4.20 4.40 4.60 4.80 MRM of 8 Channels ES181.9 > 105.9 ( tangjinna) 2.77e4 1.60 1.80 2.00 2.20 2.40 2.60 2.80 3.00 3.20 3.40 3.60 3.80 4.00 4.20 4.40 4.60 4.80 MRM of 8 Channels ES181.9 > 42 ( tangjinna) 2.44e4 1.60 1.80 2.00 2.20 2.40 2.60 2.80 3.00 3.20 3.40 3.60 3.80 4.00 4.20 4.40 4.60 4.80 MRM of 8 Channels ES177.9 > 79.9 (tianmisu) 1.23e5 1.60 1.80 2.00 2.20 2.40 2.60 2.80 3.00 3.20 3.40 3.60 3.80 4.00 4.20 4.40 4.60 4.80 MRM of 8 Channels ES161.8 > 82 (ansaimi) 1.49e5 1.40 1.60 1.80 2.00 2.20 2.40 2.60 2.80 3.00 3.20 3.40 3.60 3.80 4.00 4.20 4.40 4.60 4.80 MRM of 8 Channels ES161.8 > 77.9 (ansaimi) 1.72e4 1.40 1.60 1.80 2.00 2.20 2.40 2.60 2.80 3.00 3.20 3.40 3.60 3.80 4.00 4.20 4.40 4.60 1.45 % 100 0 0.20 20160502T3std1-6 0.40 0.60 0.80 1.00 1.20 1.40 1.45 % 100 0 0.20 20160502T3std1-6 0.40 0.60 0.80 1.00 1.20 1.40 1.57 % 100 0 0.20 20160502T3std1-6 0.40 0.60 0.80 1.00 1.20 1.40 1.321.33 % 100 1.17 0 0.20 20160502T3std1-6 0.40 0.60 0.80 1.00 1.20 1.33 % 100 1.18 0 Time 0.20 0.40 0.60 0.80 1.00 1.20 4.80 — 5ng/mL 20160501std12 MRM of 8 Channels ESTIC 9.26e3 1.33 100 3.82 3.81 3.78 1.96 3.86 3.60 3.51 3.87 3.44 1.89 1.59 % 3.28 3.90 3.01 3.17 1.99 2.51 1.46 3.98 2.81 2.79 2.95 2.69 4.05 4.09 1.62 4.20 4.22 1.69 4.23 0.29 0.09 0.47 0.85 1.16 0.80 1.20 4.27 4.42 4.54 4.77 4.88 0 Time 0.25 0.50 0.75 1.00 1.25 1.50 1.75 2.00 2.25 2.50 2.75 3.00 3.25 3.50 3.75 4.00 4.25 4.50 4.75 5ng/mL 20160501std12 1.96 % 100 0 0.09 0.29 0.47 0.62 0.25 20160501std12 0.50 0.85 0.75 1.20 1.33 1.491.51 1.00 1.25 1.50 1.89 1.75 2.00 3.60 3.78 3.82 3.86 4.05 4.20 3.01 3.28 3.44 2.51 2.73 2.81 2.25 2.50 2.75 3.00 3.25 2.25 2.50 2.75 3.00 3.25 2.50 2.75 3.00 2.50 2.75 1.99 4.00 4.25 4.50 4.75 MRM of 8 Channels ES292.9 > 260.9 (asibatian) 2.34e3 3.50 3.75 4.00 4.25 4.50 4.75 MRM of 8 Channels ES292.9 > 200.1 (asibatian) 1.19e3 3.25 3.50 3.75 4.25 4.50 4.75 MRM of 8 Channels ES181.9 > 105.9 ( tangjinna) 917 3.25 3.50 3.75 % 3.47 0 0.25 20160501std12 0.50 0.75 1.00 1.25 1.50 1.75 1.89 1.91 2.08 % 100 0 0.25 20160501std12 0.50 0.75 1.00 1.25 % 100 % 0 1.24 0.30 0 0.25 20160501std12 100 2.00 0.15 0.50 0.75 1.00 1.50 1.46 1.48 1.25 1.44 0.21 0.25 20160501std12 0.47 0.50 1.50 1.00 1.25 3.98 2.00 2.25 2.00 2.25 2.84 3.01 2.36 1.72 1.75 3.00 4.00 3.88 4.23 4.00 1.75 1.50 1.87 2.01 2.15 1.75 2.49 2.55 2.60 2.87 2.99 3.71 3.18 3.60 3.82 4.50 4.75 MRM of 8 Channels ES181.9 > 42 ( tangjinna) 631 4.51 4.01 % 4.76 4.98 2.00 2.25 2.50 2.75 3.00 3.25 3.50 3.75 4.00 4.25 4.50 4.75 MRM of 8 Channels ES177.9 > 79.9 (tianmisu) 3.71e3 4.50 4.75 MRM of 8 Channels ES161.8 > 82 (ansaimi) 7.63e3 Time 4.50 4.75 1.59 1.62 100 4.86 4.25 1.47 0.75 0.92 1.09 0.75 1.75 4.77 3.75 1.90 1.92 100 3.50 MRM of 8 Channels ES395 > 395 (sanlvzhetang) 8.20e3 4.54 4.42 0 0.25 20160501std12 0.50 0.75 1.00 1.25 1.50 1.75 2.00 2.25 2.50 2.75 3.00 3.25 3.50 3.75 4.00 4.25 1.50 1.75 2.00 2.25 2.50 2.75 3.00 3.25 3.50 3.75 4.00 4.25 1.33 100 % 1.26 0 0.25 0.50 0.75 1.00 1.25 _________________________________